HazMat Tool — substance information
Pentafluoroethane or Refrigerant gas R 125
HMT 15 June 2026- UN / ID
- UN 3220
- Hazard class
- 2.2
- Packing group
- —
- ERG guide
- ERG 126
- Special provisions
- SP T50
- Source
- 49 CFR §172 (15 June 2026)
Pentafluoroethane or Refrigerant gas R 125
Pentafluoroethane is a fluorocarbon with the formula CF3CHF2. Pentafluoroethane is currently used as a refrigerant (known as R-125) and also used as a fire suppression agent in fire suppression systems. Pentafluoroethane does not deplete ozone so it has replaced earlier fluorinated chemicals that did. However while it has zero ozone depletion potential, it has high global warming potential, reported by the United States Environmental Protection Agency (EPA), and others as 3450 times that of carbon dioxide Wikipedia
| Emergency Response Guide No. 126 |
Hazardous Materials Table
Source: 49 CFR §172 (15 June 2026)(3) Hazard Class2.2Non-toxic, non-flammable gases |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(7) Special Provisions (§172.102)
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| T50 |
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(8) Packing Authorizations (§173.***) 
| (8A) Exceptions | 306 | see 49 CFR §173.306 |
|---|---|---|
| (8B) Non-bulk | 304 | see 49 CFR §173.304 |
| (8C) Bulk | 314, 315 | see 49 CFR §173.314, 315 |
(9) Quantity Limits 
| (9A) Passenger aircraft/rail | 75 kg |
|---|---|
| (9B) Cargo aircraft only | 150 kg |
(10) Vessel stowage 
| (10A) Location | |
|---|---|
| (10B) Other | n/a |
Segregation chart for load, transport, and storage
This chart shows whether loading, transport, or storage with other hazard classes is permitted, prohibited, or restricted. Based on 49 CFR §177.848.
| Hazard class | 8![]() | 7![]() | 6.1![]() | 5.2![]() | 5.1![]() | 4.3![]() | 4.2![]() | 4.1![]() | 3![]() | 2.3B![]() | 2.3A![]() | 2.2![]() | 2.1![]() | 1.6![]() | 1.5![]() | 1.4![]() | 1.3![]() | 1.1/1.2![]() |
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2.1 ![]() | ||||||||||||||||||
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3 ![]() | ||||||||||||||||||
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7 ![]() | ||||||||||||||||||
8 ![]() |
| Must not be loaded, transported, or stored together in the same vehicle or facility. | |
| May be loaded, transported, or stored together. | |
| May be loaded, transported, or stored together only with restrictions. |